Wednesday, January 31, 2018 - 10:54

Efraim Racker said "don't waste clean thinking on dirty enzymes." Sometimes tagging a protein with histidines isn't good enough with respect to protein purity. The BFF has experience with protein expression, purification and polishing to get your protein prep as "clean" as it can be. We can use our suite of fermentors & bioreactors to produce your protein of interest typically at higher expression levels than shake flasks, then use our automated equipment to process the expressed protein.  The following is a typical process work-flow:


Stage 0 Process Development

The BFF has small-scale fermentors where we can test different conditions to come up with the optimal process for your construct.

... Read Full Article

Wednesday, November 29, 2017 - 08:53


Dr. Claire Edwards, a Postdoctoral Research Associate at the BFF, attended the Recent Advancements in Fermentation Technology (RAFT) conference hosted by the Society for Industrial Microbiology and Biotechnology (SIMB).  The conference took place October 29 through November 1, 2017 in Bonita Springs, Florida.  Claire attended a number of seminars on topics ranging from improvement of oxygen transfer rates to the fermentative production of a heme-bound protein for making meat-less burgers.

She was also able to present some of her work during the first evening’s poster presentation session.  Claire has been working on fermentation process optimization for Thermus thermophilus.  This genus is known for its ability to grow at high temperatures and you may be familiar with Thermus aquaticus, the strain... Read Full Article

Tuesday, July 11, 2017 - 09:04


Tariq Taylor (in purple shirt) at the Forum 

The Bioexpression and Fermentation Facility is proud to announce that our very own Tariq Taylor was chosen as a summer fellow at this year’s Bio-Link National Summer Fellows Forum. Each year attendees gather at the University of California, Berkeley for a week-long meeting that focuses on workforce development and training of students at various levels to serve the biotechnology industry.


At the Bio-Link National Summer Fellows Forum, participants learn new skills and techniques, examine and test exemplary curriculum models and course materials, discuss ethical, legal, and social issues in biotechnology and learn how to disseminate this information within their own regions. Fellows are expected to implement new strategies into their own programs, to lead regional staff... Read Full Article

Monday, June 12, 2017 - 15:18

TampaThe 5th annual meeting of the Southeastern Association of Shared Resources was held in Tampa, FL June 7 - 9.  The purpose of the SEASR meeting is to provide a regional forum for core directors and staff to meet and discuss the issues related to core facilities.

Each year, a poster session is held to highlight research at the attendees home institutions.  I am proud to annouce that Ruth Davis of the Bioexpression and Fermentation Facility Monoclonal Antibody Group won this year's competition.  She will receive $500 which can be applied towards attendance at next year's meeting in Atlanta.  Her poster can be downloaded here

Thursday, January 19, 2017 - 09:01

HeLa-I.jpgThe Bioexpression and Fermentation Facility is participating in a cancer reproducibility study in cooperation with Science Exchange and the Center for Open Science.  Many labs have been involved and a report from NPR suggests that there are problems with reproducing work done in the original study.  As described in the NPR report, previously, Amgen and Bayer had reported issues with reproducibility.  The Cancer Reproducibility Study was developed to further evaluated those findings with the goal of "Through independent direct replication studies, the project aims to identify best practices that maximize reproducibility and facilitate an accurate accumulation of knowledge,... Read Full Article

Tuesday, August 16, 2016 - 08:15

TangenX.jpgThe Bioexpression and Fermentation Facility is pleased to announce the addition of new capabilities for its training lab.  TangenX recently donated a system capable of using 0.1 m2 membranes.  This system will be used for training students in the use of tangential flow filtration which is widely used in bioprocessing.  This system adds to the already wide array of equipment available in the training lab located in the Davison Life Sciences Complex on the campus of the University of Georgia.  The lab, which is separate from BFF operations, is used for training of undergraduate and graduate students in protein expression and purification.  Currently BCMB4030/6030 is taught to undergraduates in the Biochemistry department as well as students in... Read Full Article

Wednesday, March 16, 2016 - 12:41

Pittcon is the leading conference and exposition for laboratory science featuring new technology and scientific research. This year several folks from our team were able to attend the confernece. Here are some pictures from the outing.

ruihau.jpgimage[1].jpgimage.jpgTariq and Gabe.jpg

Pictured (in order): Ruihua, Team Picture, Michelle, Tariq & Gabe


Monday, October 12, 2015 - 16:05


Services including immunizations, fusions and production of Hybridoma in cell culture. Five mice to be immunized and the highest titer mouse would be used for a fusion. The project includes immunizations, screening by ELISA, 1 fusion, screening of hybridomas and production of 2L of supernatant using the best clone selected.

Turnaround time: 6 months once the project initiated
Standard sample requirements: 2-4 mg of immunogen
Standard deliverables: purified antibody from 2L of culture

Request a Quote for Monocolonal Antibody Service

Tuesday, October 6, 2015 - 14:18

PDW_Eppendorf_DASbox_0.jpgThe Bioexpression and Fermentation Facility recently acquired the DasBox system from Eppendorf.  The system is capable of independently controlling 4 x 250 mL bioreactors. This new capability will the BFF to accelerate process development projects in cell culture.  Along with our Celligen 310 system we will be able to develop processes and scale to 40L within the facility.  Since both systems are stirred tank reactors, scaling will be more predictable.  The parallel processing capabilities will allow for Design of Experiments (DOE) methodologies. 

What is Design of Experiments (DOE)?

Most people have faced this problem: I have a gene of interest (GOI) that I want to express, but how do I determine the best conditions for expression?  The most common way is... Read Full Article

Wednesday, September 30, 2015 - 09:19

slovenia_3158_600x450.jpgRecently I had the pleasure of presenting at the Euromabnet meeting held September 24-25 in Ljubljana, Slovenia.  Slovenia, formerly part of Yugoslavia is nestled a short drive from Venice on the Adriatic sea and bordered by Croatia, Hungary, Italy and Austria.

The Euromabnet is a consortium of antibody researchers from across Europe including, Croatia, Czech Republic, France, Germany, Hungary, Italy, Netherlands, Russia, Slovia, Spain and Great Britain.  According to their website,, “EuroMAbNet represents the first European network of laboratories linked to academic Institutions, each having an internationally recognized reputation in the production and use of monoclonal antibodies. EuroMAbNet... Read Full Article